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Serum or plasma mass concentration of total omega-3 fatty acids (including EPA and DHA)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of omega-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), found in your blood. Omega-3s are important for heart health, brain function, and reducing inflammation.

Quick summary

["Your blood levels of omega-3 fatty acids may indicate your overall intake and how well your body uses them for health benefits."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35967-9
Short code
XR tomo Elbow-L
Synonyms
XR tomo Elbow-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-tomography
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have concerns about heart health, high triglycerides, or other conditions linked to low omega-3 levels. It could also be part of a broader evaluation for chronic inflammation, cognitive function, or metabolic health.

What to Expect Before the Test

No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but this depends on your provider’s instructions. Bring any medications you’re taking to your appointment.

What the Test Involves

A blood sample will be drawn from a vein in your arm. The sample is sent to a lab to measure the total omega-3 fatty acid content in your serum or plasma.

What the Results Mean

Results are expressed in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While reference ranges vary by lab, lower levels may suggest insufficient dietary intake or absorption, while higher levels could indicate overconsumption or metabolic changes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Omega-3 Fatty Acids (Serum/Plasma)

Frequently asked questions

What does a low or high omega-3 level indicate?
Low levels may be associated with increased risk of heart disease, poor cognitive function, or higher inflammation. High levels could signal excessive intake or rare metabolic conditions, but they’re generally not harmful unless very elevated. Your provider will interpret results in the context of your overall health.
How often should I get this test?
This test is not routinely recommended for healthy individuals. It may be ordered periodically if you have specific health concerns related to omega-3 levels, such as heart disease, diabetes, or autoimmune conditions. Follow your provider’s guidance for timing and frequency.
Can I change my diet to affect these results?
Yes! Increasing omega-3-rich foods like fatty fish (salmon, mackerel), flaxseeds, walnuts, or algae-based supplements may raise your levels over time. Avoiding excessive omega-6 sources (like vegetable oils) can help balance your fatty acid profile. Always consult your provider before making dietary changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy