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Serum or Plasma Total Protein by Bromocresol Green (BCG) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins. Proteins help maintain fluid balance, support immune function, and transport nutrients.

Quick summary

["Total protein levels can indicate overall health, hydration status, or potential liver/kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36001-6
Short code
XR tomo GB
Synonyms
XR tomo GB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-tomography
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, malnutrition, or certain immune disorders. It can also help assess hydration status or monitor treatment responses.

What to Expect Before the Test

No special preparation is needed, but you may avoid certain medications (like some diuretics) if instructed. Blood is drawn from a vein, usually in your arm, and you may feel a slight pinch. The process takes about 5 minutes.

What the Results Mean

Higher-than-normal levels might suggest dehydration, inflammation, or conditions like multiple myeloma. Lower-than-normal levels could indicate malnutrition, liver disease, or kidney problems. Your results will be interpreted by your provider in the context of your overall health.

Common Conditions Linked to Protein Levels

Abnormal protein levels can signal conditions like chronic kidney disease, liver cirrhosis, severe infections, or certain cancers. They may also reflect fluid imbalances or nutritional deficiencies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What causes protein levels to be high?
High protein levels may result from dehydration, severe infections, inflammation, or certain medical conditions like multiple myeloma or kidney disease. Your provider will review your medical history and other test results to determine the cause.
What causes protein levels to be low?
Low protein levels can be due to malnutrition, liver disease, kidney problems, or conditions that affect protein production (e.g., certain cancers or autoimmune disorders). Lifestyle factors like poor diet or chronic illness may also play a role.
Do I need to fast before this test?
No fasting is required for this test. However, follow any specific instructions your provider gives you, such as avoiding certain medications or foods, if applicable.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy