Serum or plasma concentration of total bilirubin
This test measures the total amount of bilirubin, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.
["Bilirubin levels can signal liver or bile flow issues, often linked to jaundice or other health concerns."]
Key facts at a glance
- LOINC
- 26255-0
- Short code
- XR tomo IAC-R
- Synonyms
- XR tomo IAC-R
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xr-tomography
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why is this test done?
Your doctor may order this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, dark urine, pale stools, or if they suspect liver disease, gallbladder issues, or hemolytic anemia (red blood cell breakdown). It can also be part of routine liver function checks.
What does the test involve?
A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where bilirubin levels are measured. The method may involve automated chemical analysis or other standardized techniques to determine concentration.
What might abnormal results mean?
High bilirubin levels (hyperbilirubinemia) may indicate liver problems, bile duct blockages, or red blood cell disorders. Low levels are less common but could suggest certain liver conditions or medications affecting bilirubin metabolism.
How is the test prepared?
No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could affect results (like certain supplements or alcohol). Always follow your doctor’s instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: Bilirubin is a critical marker for diagnosing and monitoring liver and bile system disorders. Elevated levels often point to conditions like hepatitis, cirrhosis, gallstones, or hemolytic anemia. Low levels may rarely indicate liver dysfunction or metabolic issues, though this is less common.
Short name
Bilirubin
Frequently asked questions
What are the typical reference ranges?
Can diet or medications affect this test?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy