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Omalizumab (Anti-IgE Antibody) Level, Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of a specific antibody (IgE) in your blood that binds to a protein called omalizumab, used in certain allergy treatments.

Quick summary

["This test helps monitor how your body responds to omalizumab therapy for allergic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
36776-3
Short code
XR tomo Mastoid
Synonyms
XR tomo Mastoid
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-tomography
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Omalizumab is a medication designed to bind to IgE antibodies, which are linked to allergic reactions. This test checks the concentration of omalizumab in your serum to ensure it’s working at the right level in your bloodstream. It’s typically done to verify therapeutic effectiveness or adjust dosing if needed.

Why Might You Need This Test?

Your healthcare provider may order this test if you’re receiving omalizumab treatment for conditions like severe asthma or allergic rhinitis. It helps track whether the medication is providing the expected benefits and if your levels are within the target range for safety and effectiveness.

How Is the Test Done?

A small blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab for analysis. The test measures the amount of omalizumab protein in your serum, which is the liquid part of your blood after blood cells and clotting factors are removed.

What Are Possible Results?

Results are typically reported as a concentration value (e.g., in micrograms per milliliter). Your healthcare provider will interpret these results in the context of your treatment plan and medical history to determine if your levels are appropriate.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Antibody Test

Frequently asked questions

How often should I expect this test?
What happens if my levels are too high or too low?
If your omalizumab levels are too low, your doctor may adjust your dosage to ensure you’re receiving the correct amount for effective treatment. If levels are too high, it may indicate an issue with absorption or dosing, which could require further evaluation.
Can I eat or drink before this test?
You can typically eat and drink normally before this test unless your doctor specifies otherwise. No special preparation is usually needed, but follow any instructions provided by your healthcare provider or lab technician.
The blood draw may cause mild discomfort or bruising at the injection site, but it’s a quick and common procedure. Most people experience minimal or no pain. Rarely, there may be a slight reaction at the injection site, such as redness or swelling.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy