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Serum or plasma concentration of total protein (mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes important substances like albumin and globulins. Proteins help maintain fluid balance, support immune function, and transport nutrients.

Quick summary

["Total protein levels can indicate overall health, hydration status, or potential issues like liver disease or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37432-2
Short code
XR tomo Wrist-L
Synonyms
XR tomo Wrist-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-tomography
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a total protein test to check for conditions affecting protein production, such as liver disease, kidney disease, or certain cancers. It can also help diagnose malnutrition or evaluate long-term health in chronic illnesses.

What Does the Test Involve?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the protein content for measurement. The result is expressed in grams per deciliter (g/dL).

What Are Common Results?

Results are not always provided as a single reference range since protein levels can vary based on age, health status, and other factors. Your provider will interpret the result in relation to your specific situation.

What Might Abnormal Results Mean?

Low total protein levels may suggest conditions like liver disease, kidney problems, or severe malnutrition. High levels could indicate dehydration, multiple myeloma, or other rare conditions. Your provider will discuss these findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein is a general measure of blood protein content and is used to assess overall protein status. While it doesn’t specify which proteins are low or high, it provides a broad overview that can guide further testing if needed.

Short name

Total Protein

Frequently asked questions

Why do I need a total protein test if I feel healthy?
Even if you feel healthy, your provider may order this test to monitor chronic conditions, check for hidden health issues, or evaluate changes in your health over time. It’s a simple way to get a snapshot of your blood’s protein content.
How long does it take to get my results?
Results are typically available within a few days, depending on your lab’s processing time. Your provider will contact you once they have the results and explain what they mean for you.
Can I eat or drink anything before this test?
You can usually eat and drink normally before this test unless your provider gives specific instructions. Blood tests like this are generally not affected by food or drink, but always follow your provider’s guidance.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy