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Serum or Plasma Total Protein by Bromocresol Green (BCG) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, including albumin and other proteins like globulins. Proteins are essential for many bodily functions, including maintaining fluid balance and supporting immune responses.

Quick summary

["Total protein helps assess overall health, hydration, and potential liver or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37644-2
Short code
XR tomo Wrist-R
Synonyms
XR tomo Wrist-R
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-tomography
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein levels, such as liver disease, kidney problems, malnutrition, or dehydration. It can also help diagnose or monitor certain medical conditions like nephrotic syndrome or severe infections.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Avoid excessive alcohol or certain medications that could affect results. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab where it’s analyzed using the bromocresol green dye method to measure protein concentration.

What Do the Results Mean?

Results are reported in grams per deciliter (g/dL). Low protein levels may indicate malnutrition, liver disease, or kidney problems, while high levels could suggest dehydration, inflammation, or certain medical conditions like multiple myeloma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormally low or high protein levels can signal underlying health issues. Low protein may reflect poor nutrient absorption, chronic liver disease, or kidney dysfunction, while high protein could indicate dehydration, severe infections, or conditions like multiple myeloma. Your doctor will interpret results in the context of your overall health and symptoms.

Short name

Total Protein (BCG)

Frequently asked questions

What causes low total protein levels?
Low total protein levels can be caused by conditions like liver disease (e.g., cirrhosis), kidney disease, malnutrition, severe infections, or certain medications. It may also occur if your body isn’t absorbing nutrients properly, such as in gastrointestinal disorders.
What causes high total protein levels?
High total protein levels can result from dehydration, severe infections (like sepsis), multiple myeloma, or certain inflammatory conditions. Rarely, it may also be linked to conditions affecting the immune system or certain genetic disorders.
How often should I get this test?
The frequency depends on your health status. If you have a chronic condition like liver disease or kidney disease, your doctor may recommend regular monitoring. Otherwise, this test is often part of routine check-ups or when symptoms suggest an underlying issue.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy