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Serum Vitamin C (Ascorbic Acid) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin C (ascorbic acid) in your blood serum. Vitamin C is an essential nutrient that helps protect cells, supports immune function, and aids in wound healing.

Quick summary

["Vitamin C helps your body stay healthy and fight infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61540-1
Short code
Years vit C PhenX
Synonyms
Years vit C PhenX
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
phenx
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms of vitamin C deficiency, such as fatigue, frequent infections, or slow wound healing. It may also be used to monitor vitamin C levels in people taking supplements or those with certain medical conditions that affect nutrient absorption, like malabsorption syndromes or chronic illnesses.

What Does a Low or High Level Mean?

Low levels of vitamin C might indicate deficiency, which can weaken your immune system or cause skin problems. High levels are less common but could be due to excessive supplementation or certain medical conditions. Your results will be discussed with your doctor to determine the best next steps.

How Is This Test Done?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab where it is processed to measure vitamin C levels using a specialized analytical method.

What Are Common Causes of Low Vitamin C?

Conditions like smoking, certain medications, or malabsorption issues (such as celiac disease or Crohn’s disease) can lead to lower vitamin C levels. Dietary deficiencies, especially in areas with limited access to fresh fruits and vegetables, are also common causes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin C plays a critical role in maintaining immune function, collagen production, and antioxidant activity. Deficiency can lead to scurvy, characterized by fatigue, gum disease, and skin problems. Regular monitoring may be needed for individuals with chronic health conditions or those on long-term vitamin C supplements.

Short name

Vitamin C Level

Frequently asked questions

What are the normal reference ranges for vitamin C?
Reference ranges can vary by lab and may not be widely standardized. Your doctor will interpret your results in the context of your overall health and symptoms.
How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule.
Can I eat or drink anything before this test?
You may eat and drink normally unless your doctor specifies otherwise. Avoiding large meals or excessive fluids right before the test can help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy