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Yeast Identification in Skin by Qualitative Potassium Hydroxide (KOH) Preparation

Published: August 9, 2026Updated: August 17, 2026

A microscopy test that examines a skin scraping for yeast, using potassium hydroxide to prepare the sample.

Quick summary

["Yeast seen on this test may support a diagnosis of a superficial fungal skin infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
55317-2
Short code
Yeast Skin Ql KOH Prep
Synonyms
Yeast Skin Ql KOH Prep
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
koh-preparation
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test examines a sample taken from the skin for yeast. A potassium hydroxide (KOH) preparation is used to clear skin cells so that yeast or fungal structures can be viewed under a microscope.

Why might I need this test?

It may be ordered when a rash, scaling, redness, or other skin symptoms suggest a fungal infection. The test can help identify yeast such as Candida in skin samples.

How is the test performed?

A clinician scrapes the affected skin or the edge of a lesion and places the material on a laboratory slide. The laboratory adds KOH and examines the preparation under a microscope.

How do I prepare for the test?

No special preparation is usually required. Do not apply creams, ointments, or other skin products to the area immediately before the sample is collected unless your clinician instructs you to do so.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

If yeast is identified, it may indicate a superficial fungal infection, particularly a Candida-related skin infection. Yeast can sometimes exist on the skin without causing symptoms, so the result should be interpreted with the appearance of the rash and other clinical findings. A negative result does not completely exclude a fungal infection if the sample was limited or the infection is deeper in the skin.

Short name

Skin yeast KOH preparation

Frequently asked questions

Does a positive result mean I have a fungal infection?
It may. Finding yeast supports a fungal infection when it matches the symptoms and examination, but yeast can occasionally be present without causing disease.
What is a KOH preparation?
KOH is a chemical used to clear away skin cells during slide preparation. This makes yeast and other fungal structures easier to see under a microscope.
Does the test identify the specific type of yeast?
Usually not. This test shows whether yeast is present; additional laboratory testing may be needed to determine the exact organism.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy