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Total Protein with Albumin/Globulin Ratio (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood’s total protein levels and evaluates the balance between albumin and globulin proteins, which helps assess kidney function, liver health, and overall protein status.

Quick summary

["Check protein balance and potential organ issues with this simple blood test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104465-0
Short code
Y entero O:3 Ab Stl Ql
Synonyms
Y entero O:3 Ab Stl Ql
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Total protein in your blood reflects the combined amount of albumin and globulin proteins. Albumin is produced by your liver and helps maintain fluid balance, while globulins support immune function and transport substances like iron. The ratio between these proteins can indicate whether your kidneys are filtering properly or if your liver is functioning normally.

Why Might Your Doctor Order This Test?

Doctors may request this test if you have symptoms like swelling (edema), unexplained weight changes, fatigue, or signs of liver/kidney problems. It can also be used to monitor chronic conditions like kidney disease, liver disease, or malnutrition.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to separate and measure protein components. No special preparation is needed, but fasting may be advised for some related tests.

Common Conditions Monitored

This test helps diagnose or monitor conditions such as kidney disease (e.g., nephrotic syndrome), liver disease (e.g., cirrhosis), malnutrition, or inflammatory disorders. Abnormal results may signal protein loss, liver dysfunction, or fluid imbalances.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Protein Ratio

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider to discuss any findings.
Can I eat or drink before this test?
No special diet is required, but check with your provider if they recommend fasting for related tests. Hydration is encouraged unless advised otherwise.
What if my results are outside the normal range?
If results are abnormal, your doctor will review them with you to determine next steps, which may include additional tests or lifestyle adjustments. Never interpret results independently.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy