Total Protein with Albumin/Globulin Ratio (Serum)
This test measures your blood’s total protein levels and evaluates the balance between albumin and globulin proteins, which help support your immune system, blood clotting, and fluid balance.
["Assesses protein composition and potential imbalances that may affect health."]
Key facts at a glance
- LOINC
- 56435-1
- Short code
- Yogurt IgG4-mCnc
- Synonyms
- Yogurt IgG4-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Total protein combines albumin and globulin proteins, which are vital for transporting nutrients, maintaining blood pressure, and supporting immune function. The ratio helps identify whether albumin or globulin levels are disproportionately high or low, which can signal conditions like liver disease, kidney problems, or infections.
Why Might You Need This Test?
Your doctor may order this test to check for protein-related issues, such as malnutrition, chronic kidney disease, liver disorders, or immune system problems. It can also help monitor conditions like multiple myeloma or inflammatory diseases.
How Is the Test Performed?
A small blood sample is drawn from your arm, and the serum (liquid part of blood after clotting) is analyzed to measure total protein and the albumin-to-globulin ratio using standard laboratory techniques.
What Are Common Results?
Results are not provided with specific numeric ranges here, as they depend on your lab and health status. Your doctor will interpret the results in relation to your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test helps identify imbalances in protein levels that may indicate underlying health issues, such as malnutrition, liver or kidney disease, or immune dysfunction. High or low ratios can signal specific conditions requiring further medical evaluation.
Short name
Protein Profile
Frequently asked questions
What does a high or low total protein level mean?
How often should I get this test?
Can diet affect protein test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy