Skip to content

Zaleplon/Creatinine Mass Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that detects zaleplon, a prescription sleep medicine, and may adjust the result for urine concentration.

Quick summary

["This test can show whether zaleplon is present in the urine; a clinician should interpret the result in your situation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87776-1
Short code
Zaleplon/Creat Ur Cfm
Synonyms
Zaleplon/Creat Ur Cfm
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures zaleplon in urine. Zaleplon is a prescription medicine used to help with difficulty falling asleep. A creatinine ratio may be used to account for differences in urine concentration.

Why might I need this test?

A clinician may order this test to check for recent zaleplon exposure, monitor medication use, or assess possible drug use. The reason for testing can vary, so ask your clinician what the result is intended to show.

How is the test performed?

You provide a urine sample, which is tested in the laboratory for zaleplon. The laboratory may compare the zaleplon amount with the urine creatinine amount to help account for how concentrated or dilute the sample is.

How do I prepare for the test?

Follow any collection instructions provided by the laboratory. Usually, you collect urine in a sterile container at the specified time. Tell the clinician about when you last took zaleplon and any other medications or supplements you used.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine zaleplon/creatinine ratio

Frequently asked questions

Does a positive result mean I misused zaleplon?
No. A positive result shows that zaleplon was detected, but it does not determine why it was taken or whether it was misused. Your clinician should interpret it using the reason for the test and your medication history.
Why is creatinine included in the test?
Creatinine is used as a reference for urine concentration. Comparing zaleplon with creatinine helps reduce the effect of unusually concentrated or dilute urine.
How long after taking zaleplon might it be detected?
Detection depends on the dose, timing, urine concentration, and individual factors. Ask the laboratory or clinician how soon after a dose the sample should be collected for your specific test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy