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Serum/Plasma Protein Electrophoresis by Bromocresol Purple (BCP) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood, helping identify abnormalities in protein levels that may signal conditions like multiple myeloma, liver disease, or kidney problems.

Quick summary

["This test helps doctors check for unusual protein patterns that could indicate hidden health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100841-6
Short code
Zic4 Ab CSF Ql Line blot
Synonyms
Zic4 Ab CSF Ql Line blot
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test separates blood proteins into categories—such as albumin, globulins, and other fractions—using a technique called electrophoresis. Bromocresol purple dye binds to proteins, allowing for visual differentiation of each protein group based on their size and charge.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if they suspect conditions like multiple myeloma (cancer of plasma cells), chronic liver disease, kidney disease, or certain autoimmune disorders. It can also help monitor treatment progress for these conditions.

How Is the Sample Collected?

A small blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum or plasma for testing.

What Are Common Results and Findings?

Results show the relative amounts of each protein fraction. For example, an abnormal spike in one fraction (like monoclonal bands in multiple myeloma) or a shift in albumin-to-globulin ratio may indicate underlying health concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a key role in diagnosing and managing conditions affecting protein production or breakdown. It helps detect hidden protein abnormalities that might not show up in routine blood tests, guiding treatment decisions for conditions like cancer, liver disease, or immune disorders.

Short name

Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test show?
It shows the breakdown of different protein types in your blood, helping identify if any protein levels are unusually high or low, which can signal conditions like cancer, liver or kidney disease, or other health issues.
How long does it take to get results from this test?
Results are typically available within 24 to 72 hours, depending on lab processing times and any follow-up steps needed.
Can I eat or drink before this test?
No special preparation is usually needed, but follow your doctor’s instructions if they provide any specific guidelines for your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy