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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a waste product from the breakdown of red blood cells. Bilirubin helps your liver process and remove waste from your body.

Quick summary

["Bilirubin helps diagnose liver and bile duct issues, including jaundice."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109098-4
Short code
Zic4 Ab Msmt Ser
Synonyms
Zic4 Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order a total bilirubin test to check for liver disease, bile duct blockages, or conditions like hemolytic anemia, where red blood cells break down faster than usual. It can also help monitor treatment progress or detect early signs of liver problems.

What to expect before the test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if your doctor specifies it. Bring any medications you’re taking and let your lab staff know if you’re pregnant or have allergies.

What happens during the test?

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a quick pinch, but it usually doesn’t cause significant discomfort. The blood sample is then sent to a lab for analysis.

What do results mean?

Higher than expected levels may suggest liver disease, bile duct problems, or red blood cell disorders. Lower levels might indicate liver dysfunction or certain genetic conditions. Your doctor will interpret results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
If fasting is required, avoid food and liquids (except water) for 8–12 hours before the test. If no fasting is needed, you can eat and drink normally. Always follow your doctor’s instructions.
What if I’m pregnant or breastfeeding?
If you’re pregnant or breastfeeding, let your doctor know before the test. Some lab tests may need adjustments to ensure safety for both you and your baby.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy