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Zinc 24-Hour Urine Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of zinc excreted in urine collected over 24 hours, which can reflect how much zinc is being absorbed and eliminated by the body.

Quick summary

["A 24-hour urine zinc measurement helps assess zinc status and urinary zinc loss when evaluated alongside diet, other labs, and clinical findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34388-9
Short code
Zinc 24h Ur-sCnc
Synonyms
Zinc 24h Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Zinc is an essential trace mineral involved in immune function, wound healing, growth, and many enzyme reactions. A 24-hour urine zinc test measures the total amount of zinc excreted in urine over a full day, which reflects both dietary intake and how the kidneys handle zinc.

Why a 24-Hour Collection Is Used

Zinc excretion varies throughout the day, so a single urine sample may not represent average output. Collecting all urine over 24 hours provides a more representative estimate of daily urinary zinc loss than a spot sample.

How to Prepare

Your care team will give specific collection instructions, including when to start and end the collection and whether to avoid any supplements or foods beforehand. Follow those instructions carefully, because incomplete or improperly timed collection can make results unreliable.

What Results Can Suggest

Urinary zinc can be affected by diet, supplements, kidney function, and other health conditions. Results are interpreted by a clinician in the context of symptoms, dietary history, and other laboratory tests rather than by a single number alone.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Urinary zinc measurement is used as one part of evaluating zinc status and suspected deficiencies or excesses, and it may also help assess conditions affecting renal handling of trace minerals. It is not diagnostic by itself; clinicians interpret it with serum or plasma zinc, dietary information, symptoms, and other relevant tests.

Short name

24-Hour Urine Zinc

Frequently asked questions

Do I need to fast for a 24-hour urine zinc test?
Fasting requirements vary by laboratory and clinical situation. Follow the specific instructions provided by your ordering clinician or collection facility.
Can supplements affect my urine zinc result?
Yes. Zinc-containing supplements and some foods can influence urinary zinc. Tell your clinician about all supplements and medications, and follow any pre-test instructions you are given.
What does a high or low urine zinc level mean?
Urine zinc results can be influenced by intake, absorption, kidney function, and other health factors. A high or low result does not by itself diagnose a condition; your clinician will interpret it alongside your symptoms, diet, and other test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy