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Zinc and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

This test measures zinc and creatinine in urine collected over 24 hours. It can help assess zinc excretion and check the adequacy of the urine collection.

Quick summary

["The test shows how much zinc your body is losing in urine and whether the 24-hour collection appears complete."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27201-3
Short code
Zinc/Creat 24h Ur
Synonyms
Zinc/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of zinc and creatinine in all urine collected during a 24-hour period. Zinc is an essential mineral, while creatinine helps clinicians evaluate urine concentration and whether the collection may be incomplete.

Why might I need this test?

A clinician may order this test to evaluate zinc status, investigate unusually high or low zinc loss, or monitor certain supplements or exposures. It may also be used when symptoms suggest a mineral deficiency or when kidney function affects mineral handling.

How is the test performed?

You collect all urine for a full 24 hours in the container provided by the laboratory. The laboratory then measures zinc and creatinine in the collected sample and may report the amount excreted over the full day.

How do I prepare for the test?

Follow the laboratory's collection instructions, including the designated start and end times. Keep the container tightly closed, store it as directed, and record any urine that is accidentally missed because an incomplete collection can affect the results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Zinc and Creatinine

Frequently asked questions

Do I need to change my diet or medications before this test?
Do not stop supplements or change your diet unless your clinician instructs you to do so. Tell the clinician about all supplements, medications, and occupational metal exposures because they can affect the result.
What happens if I miss part of the 24-hour urine collection?
Tell the laboratory, because a missed collection can make the 24-hour zinc result less reliable. Follow the laboratory's instructions about whether to restart the collection.
Does this test show whether I have a zinc deficiency?
Not by itself. Urine zinc can provide useful information, but a clinician may consider blood zinc, symptoms, diet, medications, and other tests when evaluating zinc status.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy