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Zinc in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of zinc, a mineral essential for many bodily functions, in your blood serum. Zinc helps support immune function, wound healing, and proper taste and smell.

Quick summary

["Zinc levels can help assess nutritional status or identify potential deficiencies or excesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
27125-4
Short code
Zinc RBC-mCnt
Synonyms
Zinc RBC-mCnt
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order a serum zinc test if you have symptoms like frequent infections, slow wound healing, hair loss, or changes in taste and smell. It may also be used to check for zinc deficiency in people with certain medical conditions, like Crohn’s disease or malabsorption disorders, or in those who take certain medications that can affect zinc absorption.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Wear a loose shirt for easy access to your arm.

What Happens During the Test?

A healthcare professional will insert a small needle into your arm to draw blood. The process takes just a few minutes, and you may feel a brief pinch. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are typically reported as a mass concentration (e.g., micrograms per deciliter). Your provider will interpret the results in relation to your overall health and medical history.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low zinc levels may indicate malnutrition, chronic illness, or conditions affecting zinc absorption. High levels could suggest liver disease, kidney problems, or certain medications. Zinc is also important for immune function, so monitoring levels can help prevent complications in people with weakened immune systems.

Short name

Serum Zinc Level

Frequently asked questions

What causes low zinc levels?
Low zinc levels can result from poor diet (low intake of foods like meat, shellfish, or fortified grains), digestive issues that prevent absorption, chronic illnesses (like Crohn’s disease or diabetes), or certain medications. Rarely, genetic disorders may also play a role.
How is zinc deficiency treated?
Treatment often involves dietary changes (adding zinc-rich foods) or supplements under medical supervision. Severe deficiencies may require oral or intravenous zinc therapy.
Can high zinc levels be dangerous?
Very high zinc levels are uncommon in healthy individuals but may occur with long-term zinc supplement use or certain medical conditions. Excessive zinc can interfere with iron absorption and may cause nausea or diarrhea.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy