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Protein Electrophoresis, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum using electrophoresis, a method that separates proteins based on size and electrical charge.

Quick summary

["Electrophoresis helps identify abnormal protein patterns, which may signal conditions like multiple myeloma or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2893-6
Short code
ZPP Bld Ql
Synonyms
ZPP Bld Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does the Test Measure?

Electrophoresis splits proteins into fractions (e.g., albumin, globulins) based on their movement through an electric field. This helps detect abnormal protein bands or shifts that may indicate disease.

Why Might You Need This Test?

Your doctor may order this test to diagnose or monitor conditions like multiple myeloma, lymphoma, or kidney disease, where protein levels or patterns differ from normal.

Sample Collection and Preparation

A blood sample is drawn, and serum (liquid part after clotting) is separated for testing. Results are compared to standard patterns to identify any irregularities.

Common Conditions Monitored

Abnormal findings may signal conditions such as monoclonal gammopathy (excess of one type of protein), liver disease, or immune system disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Protein electrophoresis is critical for diagnosing and managing conditions where protein abnormalities are key indicators. For example, it can reveal monoclonal spikes in multiple myeloma or identify liver dysfunction by assessing albumin/globulin ratios.

Short name

Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test involve?
It involves running your blood serum through an electric field to separate proteins into distinct bands. These bands are then analyzed for size, quantity, and patterns.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times and any follow-up testing needed.
Can I eat or drink before this test?
No special diet is required, but avoid alcohol for 24 hours before the test, as it may affect protein levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy