Aceclidine
Aceclidine is an ophthalmic cholinergic medication that causes pupil constriction (miosis) by stimulating muscarinic receptors on the iris sphincter muscle. It is used primarily during ophthalmic procedures and for conditions requiring controlled pupil reduction. The drug is designed to minimize ciliary muscle stimulation, reducing unwanted accommodation effects.
Aceclidine is a topical eye medication that constricts the pupil by stimulating muscarinic receptors in the iris.
Key facts at a glance
- ATC
- S01EB08
- RxNorm
- 2721766
- Generic
- Aceclidine
- Class
- atc-s01
- Brands
- Vizz
- Availability
- rx
- Lactation
- unknown
- Routes
- ophthalmic
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
second trimesteruse lowest effective dose
use only if benefits outweigh potential risks
regular prenatal checkups
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse lowest effective dose
use only if benefits outweigh potential risks
regular fetal monitoring
Use with caution and monitor for adverse effects.
lactation
breastfeedingno adjustment needed
consult physician before use - minimal systemic absorption expected
monitor infant for unusual symptoms
Use with caution and monitor for adverse effects.
pediatric_age
children under 12use with extreme caution
not recommended - limited safety data available
close ophthalmic monitoring
geriatric
elderly over 65no adjustment typically required
generally safe for use in elderly patients
regular eye exams
renal_impairment
mild to moderateno adjustment needed - topical formulation
safe for use with mild to moderate renal impairment
routine monitoring
hepatic_impairment
mild to moderateno adjustment needed - topical formulation
safe for use with mild to moderate hepatic impairment
routine monitoring
Statistics and clinical data
Pharmacological class
Aceclidine is classified as a parasympathomimetic miotic agent
Mechanism of action
Acts on muscarinic receptors to cause pupil constriction
Primary indication
Used to reduce intraocular pressure in glaucoma patients
Commonly prescribed since
General prescribing information for miotic agents
Used for pupil constriction during ophthalmic examinations and surgical procedures. May be prescribed for certain types of glaucoma and other conditions requiring controlled miosis.
Acts as a muscarinic receptor agonist that selectively stimulates the iris sphincter muscle, causing it to contract and narrow the pupil. Designed to achieve pupil constriction with minimal stimulation of the ciliary muscle.
For topical ophthalmic use only. Should be administered by or under direction of an eye care professional. Contraindicated in patients with uveitis or active intraocular inflammation. May cause temporary blurred vision. Avoid touching dropper tip to prevent contamination.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy