Aceprometazine / Meprobamate
Aceprometazine/Meprobamate is a combination medication that pairs a phenothiazine antipsychotic with an anxiolytic agent. This medication is primarily prescribed in some European countries for the short-term management of anxiety disorders, tension, and nervousness. The combination provides both sedative and anxiolytic effects through complementary mechanisms.
A sedating anxiolytic combination medication used for anxiety and tension disorders.
Key facts at a glance
- RxNorm
- 1007702
- Generic
- Aceprometazine / Meprobamate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily prescribed for anxiety disorders, tension, and nervousness. May also be used as a premedication before surgical procedures due to its calming and sedative properties.
Aceprometazine acts on dopamine receptors in the brain while also possessing antihistamine properties, contributing to sedative effects. Meprobamate enhances GABAergic transmission, producing anxiolytic and muscle relaxant effects. Together, they provide synergistic calming action on the central nervous system.
May cause significant drowsiness and impair alertness; alcohol and other CNS depressants should be avoided. The meprobamate component carries a risk of dependence with prolonged use. Not available or approved in many countries including the United States. Should be used with caution in elderly patients and those with a history of substance abuse.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy