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Acetaminophen / Adiphenine

Published: July 27, 2026Updated: August 25, 2026

This combination medication pairs acetaminophen's analgesic and antipyretic properties with adiphenine's smooth muscle relaxant effects. It is designed to provide relief for pain that involves muscle spasms or cramping, particularly in the gastrointestinal or urinary tracts.

Quick summary

A combination analgesic and antispasmodic medication for treating pain associated with smooth muscle spasms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
1007223
Generic
Acetaminophen / Adiphenine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for relieving pain and discomfort associated with smooth muscle spasms, including menstrual cramps, gastrointestinal spasms, renal colic, and other conditions involving both pain and muscle cramping.

Acetaminophen provides analgesic and fever-reducing effects through cyclooxygenase inhibition, while adiphenine acts as a muscarinic antagonist to block acetylcholine receptors and relax smooth muscle tissue.

Follow dosage instructions carefully to avoid acetaminophen toxicity. Use with caution in patients with liver disease, glaucoma, or urinary retention. Avoid alcohol during treatment. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy