Acetaminophen / Aluminum Acetate / Chlorpheniramine / Phenylpropanolamine
This combination medication contains four active ingredients that work together to relieve multiple symptoms of allergic reactions and upper respiratory conditions. Acetaminophen provides pain relief and reduces fever, chlorpheniramine addresses allergic symptoms like sneezing and itching, while phenylpropanolamine acts as a decongestant to reduce nasal stuffiness. Aluminum acetate may help with minor skin irritation and provide buffering effects.
A multi-symptom allergy and cold medication combining an antihistamine, decongestant, pain reliever, and antacid for comprehensive relief of respiratory and allergic symptoms.
Key facts at a glance
- RxNorm
- 1008157
- Generic
- Acetaminophen / Aluminum Acetate / Chlorpheniramine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion, sneezing, runny nose, itchy/watery eyes, minor aches and pains, and fever associated with allergies, common cold, or sinusitis. May also help with skin irritation when applied topically.
Chlorpheniramine blocks histamine H1 receptors to reduce allergic symptoms. Phenylpropanolamine constricts blood vessels in nasal passages to decrease congestion. Acetaminophen inhibits cyclooxygenase enzymes to relieve pain and reduce fever. Aluminum acetate has mild astringent and buffering properties.
May cause drowsiness; avoid operating machinery or driving until you know how it affects you. Do not combine with alcohol or other sedatives. Patients with hypertension, heart disease, thyroid disorders, or glaucoma should use caution. Do not exceed recommended dose; acetaminophen overdose can cause serious liver damage. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy