Acetaminophen / Aspirin
This combination medication pairs two well-established analgesics to provide relief from pain and fever. It is typically used for temporary relief of minor aches, headaches, and fever symptoms. This multi-ingredient approach may offer enhanced pain relief compared to either component alone.
A combination analgesic for temporary relief of mild to moderate pain and fever.
Key facts at a glance
- RxNorm
- 687078
- Generic
- Acetaminophen / Aspirin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to temporarily relieve minor aches and pains, headaches, muscle aches, backaches, toothaches, and fever associated with common conditions like colds or flu.
Acetaminophen works primarily in the brain to reduce pain perception and fever, while aspirin inhibits cyclooxygenase enzymes to decrease pain-signaling prostaglandins and reduce inflammation. Together they may provide complementary analgesic effects.
Should not be used in children or teenagers recovering from viral infections due to Reye's syndrome risk (from aspirin component). Patients with liver disease, stomach ulcers, or bleeding disorders should consult a healthcare provider before use. Avoid alcohol during treatment. Do not use for more than 10 days for pain or 3 days for fever without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy