Acetaminophen / Aspirin / Salicylamide
This multi-ingredient analgesic combines three pain-relieving and fever-reducing ingredients: acetaminophen, aspirin, and salicylamide. It is typically used for the temporary relief of mild to moderate pain, headaches, fever, and discomfort associated with common illnesses like colds or flu. The combination works synergistically to address multiple pain pathways.
A triple-action pain reliever and fever reducer combining acetaminophen, aspirin, and salicylamide for enhanced relief of various aches and fever.
Key facts at a glance
- RxNorm
- 820701
- Generic
- Acetaminophen / Aspirin / Salicylamide
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves minor aches and pains associated with headaches, toothaches, muscle aches, backaches, arthritis, colds, flu, and menstrual cramps, and reduces fever.
Each ingredient works through different mechanisms: acetaminophen reduces pain signals in the central nervous system, aspirin and salicylamide inhibit cyclooxygenase (COX) enzymes to decrease prostaglandin production, providing anti-inflammatory effects in addition to pain and fever relief.
This product contains aspirin and should not be used by children or teenagers recovering from viral infections due to Reye's syndrome risk. Avoid alcohol while taking this medication as it may increase liver toxicity risk. Those with aspirin allergies, bleeding disorders, or who take blood thinners should consult a healthcare provider before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy