Acetaminophen / Atropine / Chlorpheniramine / Phenylephrine
This combination medication contains four active ingredients that work together to relieve multiple cold and allergy symptoms. Acetaminophen provides pain relief and fever reduction, chlorpheniramine addresses allergic symptoms like sneezing and runny nose, phenylephrine acts as a nasal decongestant to reduce congestion, and atropine helps reduce excessive secretions. This medication is typically used for temporary relief of symptoms associated with the common cold, allergies, or sinus congestion.
A multi-ingredient cold and allergy medication providing relief from pain, fever, congestion, sneezing, and runny nose.
Key facts at a glance
- RxNorm
- 1008644
- Generic
- Acetaminophen / Atropine / Chlorpheniramine / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion, sinus congestion, headache, minor aches and pains, fever, runny nose, sneezing, and itchy, watery eyes associated with colds, allergies, or hay fever.
Acetaminophen reduces fever and pain; chlorpheniramine blocks histamine to relieve allergic symptoms; phenylephrine constricts blood vessels in nasal passages to reduce swelling and congestion; atropine reduces respiratory and nasal secretions.
May cause drowsiness; avoid alcohol and operating machinery until you know how it affects you. Do not use with other products containing acetaminophen. Consult a healthcare provider if you have heart disease, high blood pressure, thyroid problems, diabetes, glaucoma, or difficulty urinating due to enlarged prostate. Not recommended during pregnancy without medical advice.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy