Acetaminophen/Brompheniramine/Phenylpropanolamine
This combination medication contains three active ingredients that work together to relieve multiple cold and allergy symptoms. Acetaminophen provides pain relief and reduces fever, while brompheniramine acts as an antihistamine to address sneezing, runny nose, and itchy eyes. Phenylpropanolamine serves as a decongestant to help relieve nasal congestion.
A multi-symptom cold and allergy relief medication combining an analgesic, antihistamine, and decongestant.
Key facts at a glance
- RxNorm
- 214128
- Generic
- Acetaminophen / Brompheniramine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is used to temporarily relieve symptoms associated with the common cold, seasonal allergies, and hay fever, including headache, fever, body aches, nasal congestion, sneezing, runny nose, and itchy or watery eyes.
Acetaminophen inhibits the production of prostaglandins in the brain to reduce pain and fever. Brompheniramine blocks histamine at H1 receptors to reduce allergic symptoms. Phenylpropanolamine constricts blood vessels in the nasal passages to reduce swelling and congestion.
This medication may cause drowsiness; avoid alcohol and driving until you know how it affects you. Do not use with other products containing acetaminophen to avoid exceeding maximum daily dose. Consult a healthcare provider before use if you have high blood pressure, thyroid disease, diabetes, glaucoma, or are taking other medications. Not recommended during pregnancy without medical advice.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy