Acetaminophen/Caffeine/Chlorpheniramine
This combination medication provides relief from multiple cold and allergy symptoms. Acetaminophen reduces pain and fever, caffeine enhances the analgesic effect, and chlorpheniramine alleviates sneezing, runny nose, and itchy eyes associated with allergies.
A multi-symptom cold and allergy relief medication combining a pain reliever/fever reducer, stimulant, and antihistamine.
Key facts at a glance
- RxNorm
- 1303250
- Generic
- Acetaminophen / Caffeine / Chlorpheniramine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of symptoms associated with the common cold, flu, hay fever, or other upper respiratory allergies, including headache, fever, minor body aches, nasal congestion, sneezing, runny nose, and itchy, watery eyes.
Acetaminophen inhibits pain signals and reduces fever; caffeine constricts blood vessels in the brain to enhance pain relief; chlorpheniramine blocks histamine receptors to relieve allergic symptoms.
May cause drowsiness; avoid alcohol and operating machinery. Do not exceed the recommended dose as acetaminophen can cause liver damage. Consult a healthcare provider if symptoms persist beyond 7 days or are accompanied by fever, rash, or persistent headache.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy