Acetaminophen/Caffeine/Chlorpheniramine/Phenylpropanolamine
This combination medication is designed to relieve multiple cold and allergy symptoms simultaneously. It contains a pain reliever/fever reducer, an antihistamine for allergic reactions, a stimulant to reduce fatigue, and a decongestant for nasal stuffiness. This makes it suitable for individuals experiencing overlapping symptoms of allergies, cold, or sinus congestion.
Multi-symptom cold, allergy, and congestion relief medication combining pain relief, antihistamine, decongestant, and stimulant effects.
Key facts at a glance
- RxNorm
- 689567
- Generic
- Acetaminophen / Caffeine / Chlorpheniramine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, allergies, hay fever, and sinus congestion including headache, minor aches and pains, fever, sneezing, runny nose, itchy/watery eyes, and nasal/sinus congestion
Acetaminophen reduces pain and fever; chlorpheniramine blocks histamine to relieve allergic symptoms; phenylpropanolamine constricts blood vessels in nasal passages to reduce congestion; caffeine acts as a mild stimulant to combat drowsiness and may enhance acetaminophen's effectiveness
May cause drowsiness; avoid alcohol and operating machinery until you know how it affects you. Do not use with other acetaminophen products to prevent overdose. Consult a healthcare provider if you have high blood pressure, heart disease, thyroid disorders, diabetes, glaucoma, or urinary problems. Not recommended during pregnancy without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy