Acetaminophen / Chlorpheniramine / Dextromethorphan
Acetaminophen/Chlorpheniramine/Dextromethorphan is a combination medication that provides relief from multiple cold and allergy symptoms. Acetaminophen reduces pain and fever, chlorpheniramine addresses sneezing and runny nose as an antihistamine, and dextromethorphan suppresses coughing. This multi-ingredient formulation is commonly used by adults and children experiencing overlapping symptoms of upper respiratory infections.
A combination cold and allergy medication that relieves pain, fever, sneezing, runny nose, and cough.
Key facts at a glance
- RxNorm
- 1007587
- Generic
- Acetaminophen / Chlorpheniramine / Dextromethorphan
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication treats common cold symptoms, flu symptoms, and allergic rhinitis including headache, minor aches and pains, fever, sneezing, runny nose, itchy/watery eyes, and cough.
Acetaminophen inhibits pain and fever signals in the nervous system. Chlorpheniramine blocks histamine receptors to reduce allergic symptoms. Dextromethorphan acts on the cough center in the brain to suppress cough reflex.
Do not exceed recommended daily dose of acetaminophen to avoid liver damage. Avoid alcohol while taking this medication. May cause drowsiness; use caution when driving or operating machinery. Consult a healthcare provider before use if you have liver disease, glaucoma, enlarged prostate, or breathing problems. Not recommended for children under 6 years without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy