Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine
This multi-symptom cold and flu medication combines four active ingredients to provide relief from multiple symptoms including fever, headache, body aches, nasal congestion, sneezing, runny nose, and cough. It is typically used by adults and children seeking comprehensive relief from upper respiratory infections.
A combination cold medication that relieves fever, pain, congestion, allergies, and cough through four complementary active ingredients.
Key facts at a glance
- RxNorm
- 689580
- Generic
- Acetaminophen / Chlorpheniramine / Dextromethorphan / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, flu, or allergies including fever, headache, minor body aches, nasal congestion, sinus pressure, sneezing, runny nose, itchy throat, and cough.
Acetaminophen reduces fever and pain; chlorpheniramine blocks histamine to relieve sneezing and runny nose; dextromethorphan suppresses the cough reflex in the brain; phenylephrine constricts blood vessels in nasal passages to reduce congestion.
Do not use with other products containing acetaminophen; avoid alcohol; consult a doctor if you have high blood pressure, heart disease, thyroid disorders, diabetes, glaucoma, or breathing problems; may cause drowsiness; do not use in children under 6 years without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy