Acetaminophen / Chlorpheniramine / Phenylephrine / Phenyltoloxamine
This combination medication provides relief for multiple cold, flu, and allergy symptoms. It contains acetaminophen for pain and fever reduction, antihistamines for sneezing and runny nose, and a decongestant for nasal congestion. It is typically used by adults and children seeking relief from upper respiratory symptoms associated with allergies or the common cold.
A multi-symptom cold and allergy relief medication combining pain/fever reducer with antihistamines and a decongestant.
Key facts at a glance
- RxNorm
- 1009140
- Generic
- Acetaminophen / Chlorpheniramine / Phenylephrine / Phenyltoloxamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms of the common cold, flu, and seasonal allergies including headache, fever, minor body aches, sneezing, runny nose, itchy eyes, nasal congestion, and sinus pressure.
Acetaminophen reduces fever and pain; chlorpheniramine and phenyltoloxamine are antihistamines that block histamine to reduce allergic symptoms; phenylephrine constricts blood vessels in nasal passages to reduce congestion and swelling.
Do not exceed the recommended dose; avoid alcohol as it may increase liver side effects from acetaminophen; consult a doctor if you have high blood pressure, heart disease, thyroid disorders, diabetes, glaucoma, or prostate issues; may cause drowsiness; do not use with other acetaminophen products to avoid overdose.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy