Acetaminophen / Chlorpheniramine / Pseudoephedrine
This combination medication provides relief from multiple cold and allergy symptoms. Acetaminophen reduces pain and fever, while chlorpheniramine addresses sneezing, runny nose, and itchy eyes as an antihistamine. Pseudoephedrine helps relieve nasal and sinus congestion by reducing swelling in the nasal passages.
A multi-symptom cold and allergy relief medication combining a pain reliever, antihistamine, and decongestant.
Key facts at a glance
- RxNorm
- 689765
- Generic
- Acetaminophen / Chlorpheniramine / Pseudoephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, hay fever, and other upper respiratory allergies including headache, fever, minor body aches, nasal congestion, sinus congestion, sneezing, runny nose, and itchy nose or throat.
Acetaminophen works as an analgesic and antipyretic to reduce pain and fever. Chlorpheniramine is an antihistamine that blocks histamine receptors, reducing allergic symptoms like sneezing and runny nose. Pseudoephedrine is a nasal decongestant that constricts blood vessels in the nasal passages, reducing swelling and congestion.
This medication may cause drowsiness; avoid operating machinery or driving until you know how it affects you. Do not use with alcohol or other sedatives. Consult a healthcare provider before use if you have high blood pressure, heart disease, thyroid problems, diabetes, glaucoma, or prostate issues. Do not exceed recommended doses or use for prolonged periods without medical advice.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy