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Acetaminophen / Dexbrompheniramine / Pseudoephedrine

Published: July 27, 2026Updated: August 27, 2026

This combination medication contains an analgesic (acetaminophen), an antihistamine (dexbrompheniramine), and a decongestant (pseudoephedrine). It is commonly used to temporarily relieve symptoms associated with the common cold, allergies, or sinus congestion such as fever, headache, body aches, sneezing, runny nose, itchy eyes, and nasal or sinus congestion. The three active ingredients work together to address multiple symptoms simultaneously.

Quick summary

A multi-symptom cold and allergy relief medication combining a pain reliever, antihistamine, and decongestant.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
466517
Generic
Acetaminophen / Dexbrompheniramine / Pseudoephedrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves symptoms of the common cold, allergic rhinitis, and sinus congestion including fever, headache, minor body aches and pains, sneezing, runny nose, itchy eyes, watery eyes, and nasal or sinus congestion.

Acetaminophen reduces fever and relieves minor pain; dexbrompheniramine blocks the action of histamine to reduce allergic symptoms like sneezing and itchy eyes; pseudoephedrine constricts blood vessels in the nasal passages to reduce swelling and congestion.

Do not exceed the recommended dose as this product contains acetaminophen. Consult a healthcare provider before use if you have certain medical conditions such as heart disease, high blood pressure, thyroid disorders, diabetes, glaucoma, or urinary problems. May cause drowsiness; avoid alcohol and operating machinery until you know how the medication affects you. Not recommended for use in children under 12 years of age without medical advice.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy