Acetaminophen / Dextromethorphan / Guaifenesin / Pseudoephedrine
This combination medication provides multi-symptom relief for colds, flu, and allergies. It addresses pain, fever, cough, chest congestion, and nasal congestion through four different active ingredients. It is typically used by adults and children over a certain age when experiencing multiple cold or flu symptoms simultaneously.
A cold/flu medication combining a pain reliever, cough suppressant, expectorant, and nasal decongestant for comprehensive symptom relief.
Key facts at a glance
- RxNorm
- 689778
- Generic
- Acetaminophen / Dextromethorphan / Guaifenesin / Pseudoephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, flu, or hay fever including headache, minor aches and pains, fever, sore throat, cough, chest congestion, and nasal congestion.
Acetaminophen reduces pain and fever; dextromethorphan suppresses the cough reflex in the brain; guaifenesin helps loosen and thin mucus in the airways; pseudoephedrine constricts blood vessels in the nasal passages to reduce swelling and congestion.
Do not exceed recommended doses; avoid alcohol; consult a doctor before use if you have high blood pressure, heart disease, thyroid disorders, diabetes, or are taking other medications; stop use and seek medical attention if symptoms worsen or persist beyond 7 days.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy