Acetaminophen / Dextromethorphan / Phenylephrine
This combination medication is used to temporarily relieve multiple symptoms of colds, flu, and allergies including fever, headache, sore throat, minor aches and pains, cough, nasal congestion, and sinus congestion/pressure. It is typically taken by mouth in liquid, tablet, or capsule form as needed for symptom relief.
A multi-symptom cold and flu relief medication combining a pain reliever/fever reducer, cough suppressant, and decongestant.
Key facts at a glance
- RxNorm
- 705259
- Generic
- Acetaminophen / Dextromethorphan / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, flu, or upper respiratory allergies including fever, headache, sore throat, minor body aches and pains, cough due to minor throat and bronchial irritation, nasal congestion, and sinus pressure and congestion.
Acetaminophen works as a pain reliever and fever reducer. Dextromethorphan suppresses the cough reflex in the brain. Phenylephrine acts as a decongestant by narrowing blood vessels in the nasal passages to reduce swelling and congestion.
Do not exceed the recommended dose or use with other acetaminophen-containing products. Consult a healthcare provider before use if you have liver disease, glaucoma, thyroid disorders, diabetes, high blood pressure, heart disease, or breathing problems. Avoid alcohol while taking this medication. Stop use and consult a doctor if symptoms worsen, new symptoms appear, or fever persists for more than 3 days.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy