Acetaminophen / Dextromethorphan / Phenylephrine / Triprolidine
This combination medication provides relief from multiple symptoms of colds, allergies, and sinus congestion. It contains four active ingredients that work together to reduce fever and pain, suppress coughing, relieve nasal congestion, and alleviate sneezing and runny nose associated with allergic reactions or upper respiratory infections.
A multi-symptom cold and allergy relief medication that combines a pain reliever, cough suppressant, decongestant, and antihistamine.
Key facts at a glance
- RxNorm
- 2173661
- Generic
- Acetaminophen / Dextromethorphan / Phenylephrine / Triprolidine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, flu, hay fever, or other upper respiratory allergies including headache, fever, minor aches and pains, sore throat, nasal congestion, sinus congestion, cough, and sneezing.
Acetaminophen reduces fever and pain; dextromethorphan suppresses the cough reflex in the brain; phenylephrine shrinks blood vessels in the nasal passages to reduce congestion; triprolidine blocks histamine to relieve sneezing, runny nose, and itchy eyes.
Do not take with other products containing acetaminophen. Avoid alcohol. May cause drowsiness; use caution when driving or operating machinery. Consult a doctor before use if you have high blood pressure, heart disease, thyroid problems, diabetes, glaucoma, or breathing problems. Not recommended for children under 6 years without medical advice.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy