Acetaminophen / Dextromethorphan / Pseudoephedrine / Pyrilamine
This multi-ingredient medication combines a pain reliever/fever reducer, cough suppressant, decongestant, and antihistamine to provide comprehensive relief from cold, flu, and allergy symptoms. It is typically used by adults and children to address congestion, coughing, body aches, fever, and sneezing in a single product.
A combination cold/flu medication that relieves multiple symptoms including pain, fever, cough, nasal congestion, and runny nose.
Key facts at a glance
- RxNorm
- 1007141
- Generic
- Acetaminophen / Dextromethorphan / Pseudoephedrine / Pyrilamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, flu, or hay fever including nasal/sinus congestion, cough, sore throat, headache, body aches, fever, runny nose, and sneezing.
Acetaminophen reduces pain and fever; Dextromethorphan suppresses the cough reflex in the brain; Pseudoephedrine constricts blood vessels in nasal passages to reduce swelling and congestion; Pyrilamine blocks histamine to relieve allergy symptoms like runny nose and sneezing.
Do not use with other acetaminophen products to avoid overdose. Consult a doctor before use if you have high blood pressure, heart disease, thyroid problems, diabetes, or are taking other medications. Avoid alcohol. Not recommended during pregnancy without medical advice. Stop use and contact a doctor if symptoms worsen or persist beyond 7 days.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy