Acetaminophen / Dextromethorphan / Triprolidine
This combination medication provides relief from multiple cold and allergy symptoms. It contains three active ingredients that work together to reduce fever and pain, suppress coughing, and alleviate nasal congestion and sneezing. This medication is typically used to treat symptoms of the common cold, flu, or allergic rhinitis.
A multi-symptom cold, flu, and allergy relief medication combining a pain/fever reducer, cough suppressant, and antihistamine.
Key facts at a glance
- RxNorm
- 2173666
- Generic
- Acetaminophen / Dextromethorphan / Triprolidine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves symptoms associated with the common cold, influenza, and allergic rhinitis, including fever, headache, sore throat, minor aches and pains, cough, nasal congestion, sneezing, and runny nose.
Acetaminophen reduces fever and relieves pain; dextromethorphan acts on the cough center in the brain to suppress coughing; triprolidine is an antihistamine that blocks the action of histamine to reduce sneezing, runny nose, and watery eyes.
Do not use with other products containing acetaminophen to avoid overdose. Avoid alcohol; may cause drowsiness. Do not use if currently taking an MAOI or for 2 weeks after stopping one. Consult a healthcare provider before use if you have liver disease, glaucoma, difficulty urinating, or are pregnant or breastfeeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy