Acetaminophen / Dihydrocodeine
Acetaminophen/Dihydrocodeine is a combination analgesic medication used to treat moderate to moderately severe pain. It combines a non-opioid pain reliever (acetaminophen) with an opioid component (dihydrocodeine) to provide enhanced pain control when simpler analgesics are insufficient. This medication is typically prescribed for short-term use following surgery, injury, or severe dental pain.
A prescription combination pain medication pairing an opioid with acetaminophen for moderate to severe pain relief.
Key facts at a glance
- RxNorm
- 151196
- Generic
- Acetaminophen / Dihydrocodeine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Management of moderate to moderately severe pain when other non-opioid analgesics have not provided adequate relief. Commonly used for post-operative pain, injury-related pain, and severe dental pain.
Dihydrocodeine is an opioid analgesic that binds to mu-opioid receptors in the brain and spinal cord, altering the perception of pain. Acetaminophen works centrally to reduce pain sensation and fever. The combination provides synergistic analgesic effects greater than either component alone.
Contains an opioid with risk of dependence, tolerance, and addiction. High acetaminophen content poses risk of liver toxicity, especially with alcohol use or pre-existing liver disease. May cause drowsiness, dizziness, and respiratory depression—use caution when operating machinery. Not recommended for long-term use. Avoid combining with other CNS depressants.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy