Acetaminophen / Dimenhydrinate
Acetaminophen/Dimenhydrinate is a combination medication that pairs an analgesic and fever reducer with an anti-nausea agent. This medication is typically used to treat symptoms of motion sickness, including dizziness, nausea, and associated headaches or minor aches and pains. It is commonly used by travelers, those prone to motion sickness, or individuals experiencing nausea with concurrent mild pain or fever.
A motion sickness relief medication that also addresses associated pain and fever symptoms.
Key facts at a glance
- RxNorm
- 1006970
- Generic
- Acetaminophen / Dimenhydrinate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of motion sickness symptoms including nausea, vomiting, dizziness, and vertigo. Also provides relief from associated headaches and minor aches and pains that may accompany motion sickness or nausea.
Acetaminophen works by inhibiting prostaglandin synthesis in the central nervous system to reduce pain and fever. Dimenhydrinate is an antihistamine that blocks H1 receptors in the vomiting center of the brain and affects the inner ear balance mechanisms to prevent nausea and dizziness associated with motion sickness.
May cause drowsiness; avoid operating machinery or driving until knowing how medication affects you. Should not be combined with alcohol or other CNS depressants. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications. Do not exceed recommended doses as acetaminophen can cause liver damage.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy