Acetaminophen / Hydrocodone
Acetaminophen/Hydrocodone is a combination medication that combines an opioid pain reliever (hydrocodone) with a non-opioid analgesic (acetaminophen) to treat moderate to moderately severe pain. It works by altering the way the brain and nervous system respond to pain while also reducing fever. This medication is typically prescribed when other pain management options have been insufficient.
A prescription opioid combination medication used to manage moderate to severe pain.
Key facts at a glance
- RxNorm
- 214182
- Generic
- Acetaminophen / Hydrocodone
- Class
- multi-ingredient
- Brands
- Verdrocet, Norco, Hycet
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of moderate to moderately severe pain that requires an opioid analgesic and where other pain medications have not provided adequate relief.
Hydrocodone binds to opioid receptors in the brain and spinal cord to reduce pain perception, while acetaminophen inhibits prostaglandin production in the brain to enhance pain relief and reduce fever.
This is a Schedule II controlled substance with risk of dependence, addiction, and overdose. Avoid alcohol as it increases risk of liver damage from acetaminophen. May cause drowsiness, dizziness, or respiratory depression. Never exceed the maximum daily dose of acetaminophen (4g) to prevent serious liver injury. Use exactly as prescribed by your healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy