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Acetaminophen / Ketoprofen

Published: July 27, 2026Updated: August 27, 2026

Acetaminophen/Ketoprofen is a combination medication that pairs an analgesic-antipyretic with a nonsteroidal anti-inflammatory drug (NSAID) to provide pain relief and reduce inflammation. This combination is typically used for the short-term treatment of mild to moderate pain, such as headaches, muscle aches, dental pain, or pain associated with minor arthritis.

Quick summary

A combination pain reliever and anti-inflammatory medication used for short-term treatment of various mild to moderate pain conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1008935
Generic
Acetaminophen / Ketoprofen
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of mild to moderate pain including headaches, muscle aches, back pain, dental pain, menstrual cramps, and minor arthritis pain. May also be used for fever reduction.

Acetaminophen works primarily in the central nervous system to alter the body's perception of pain and helps reduce fever. Ketoprofen, an NSAID, blocks the production of natural substances called prostaglandins that cause inflammation, pain, and fever.

Avoid alcohol as it increases the risk of liver damage from acetaminophen. Do not exceed recommended doses as acetaminophen can cause serious liver injury. NSAIDs like ketoprofen may increase risk of heart attack, stroke, and gastrointestinal bleeding. Not recommended for use during late pregnancy. Consult a doctor before use if you have liver disease, kidney disease, heart disease, or a history of stomach ulcers.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy