Acetaminophen / Loratadine / Pseudoephedrine
This combination medication contains three active ingredients that work together to relieve multiple symptoms of allergies, colds, and sinus congestion. Acetaminophen reduces pain and fever, loratadine provides antihistamine relief for sneezing, runny nose, and itchy eyes, while pseudoephedrine shrinks nasal passages to relieve congestion. This multi-ingredient approach is designed for individuals experiencing several symptoms simultaneously who want relief from pain, allergy symptoms, and congestion in a single product.
A combination cold and allergy medication that relieves pain, fever, sneezing, runny nose, itchy eyes, and nasal congestion through three different active ingredients.
Key facts at a glance
- RxNorm
- 1008083
- Generic
- Acetaminophen / Loratadine / Pseudoephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of common cold and allergy symptoms including headache, fever, minor aches, sneezing, runny nose, itchy nose or throat, watery eyes, and nasal or sinus congestion.
Acetaminophen is an analgesic and antipyretic that reduces pain and fever. Loratadine is a second-generation antihistamine that blocks histamine to reduce allergic symptoms. Pseudoephedrine is a nasal decongestant that shrinks blood vessels in the nasal passages to relieve stuffiness.
Do not use with other products containing acetaminophen as this may increase risk of liver damage. Pseudoephedrine may raise blood pressure and heart rate; consult a doctor if you have heart disease, high blood pressure, thyroid problems, diabetes, or prostate issues. Avoid in first trimester of pregnancy. May cause drowsiness in some individuals despite loratadine being non-drowsy for most.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy