Acetaminophen / Meperidine
Acetaminophen/Meperidine is a combination analgesic that pairs an opioid with a non-opioid pain reliever to manage moderate to severe pain requiring stronger analgesia. This medication is used when single-agent pain relief is insufficient.
A combination opioid/non-opioid medication for treating moderate to severe pain.
Key facts at a glance
- RxNorm
- 689788
- Generic
- Acetaminophen / Meperidine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Management of moderate to severe pain, typically used when other analgesics are inadequate. May be prescribed for acute pain such as post-surgical discomfort or injury-related pain.
Meperidine acts on mu-opioid receptors in the central nervous system to alter pain perception, while acetaminophen inhibits prostaglandin synthesis to provide additional analgesic and antipyretic effects.
Due to meperidine's metabolite normeperidine, this medication is generally limited to short-term use. Contains opioid properties with risks of dependence, sedation, and respiratory depression. Avoid in patients with renal impairment, seizure disorders, or those taking MAO inhibitors.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy