Acetaminophen / Mephenesin
This medication combines acetaminophen, an analgesic and fever reducer, with mephenesin, a muscle relaxant that acts on the central nervous system. The combination is designed to relieve pain associated with muscle tension, spasms, and musculoskeletal conditions. It is typically used when pain is accompanied by muscle stiffness or involuntary muscle contractions.
A combination analgesic and muscle relaxant for treating pain associated with muscle tension and spasms.
Key facts at a glance
- RxNorm
- 818306
- Generic
- Acetaminophen / Mephenesin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of pain and discomfort associated with muscle tension, spasms, muscle strains, back pain, tension headaches, and other musculoskeletal conditions where both pain relief and muscle relaxation are needed.
Acetaminophen works in the central nervous system to reduce pain perception and fever, while mephenesin acts as a central muscle relaxant that blocks nerve impulses or muscle contractions causing spasms, providing a dual therapeutic effect.
Do not exceed recommended doses to avoid liver damage (acetaminophen component). May cause drowsiness or dizziness; avoid alcohol and operating machinery until you know how it affects you. Not recommended during pregnancy or breastfeeding without medical advice. Consult a healthcare provider if pain persists beyond recommended duration.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy