Acetaminophen / Phenylpropanolamine
Acetaminophen/Phenylpropanolamine is a combination medication used to temporarily relieve symptoms of the common cold, flu, and allergies. Acetaminophen works as an analgesic and fever reducer while phenylpropanolamine acts as a nasal decongestant to reduce swelling in the nasal passages.
A combination cold and flu remedy that relieves pain, fever, and nasal congestion through its dual-action formula.
Key facts at a glance
- RxNorm
- 689796
- Generic
- Acetaminophen / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves nasal congestion, sinus pressure, headache, minor aches and pains, and fever associated with the common cold, flu, or allergies.
Acetaminophen inhibits pain signals and reduces fever by acting on the hypothalamus, while phenylpropanolamine constricts blood vessels in the nasal passages, reducing swelling and congestion.
This product has been withdrawn from the market in several countries due to stroke risk associated with phenylpropanolamine. Consult current local availability and warnings. Do not use with other acetaminophen products to avoid overdose. Avoid in patients with hypertension, heart disease, thyroid disorders, or glaucoma. Not recommended for children.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy