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Acetaminophen / Phenyltoloxamine

Published: July 27, 2026Updated: August 27, 2026

Acetaminophen/Phenyltoloxamine is a combination medication that provides relief from mild to moderate pain and fever. The acetaminophen component works as an analgesic and antipyretic, while phenyltoloxamine, an antihistamine, may help address tension-related symptoms. This combination is commonly used for headaches, body aches, and fever associated with colds or allergies.

Quick summary

A pain reliever and fever reducer combined with an antihistamine for headache and tension relief.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
219228
Generic
Acetaminophen / Phenyltoloxamine
Class
multi-ingredient
Brands
Contragesic, Relagesic, Dologesic
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporary relief of mild to moderate pain, headache, body aches, fever, and symptoms associated with colds, allergies, or sinus congestion. Often used for tension headaches.

Acetaminophen works by blocking pain signals and reducing fever through action on the brain's temperature-regulating center. Phenyltoloxamine is an antihistamine that may help relieve tension-related symptoms and provide mild sedation.

Do not exceed recommended doses; excessive acetaminophen can cause liver damage. The antihistamine component may cause drowsiness; avoid alcohol and operating machinery until you know how the medication affects you. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy