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Acetaminophen Propyphenazone

Published: July 27, 2026Updated: August 27, 2026

Acetaminophen/Propyphenazone is a combination analgesic medication used for the relief of pain and fever. It combines two active ingredients that work through complementary mechanisms to provide effective symptomatic relief. This medication is typically prescribed when single-ingredient therapies may be insufficient for managing moderate pain or fever.

Quick summary

A combination pain reliever and fever reducer used to treat various conditions involving pain and elevated body temperature.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1007681
Generic
Acetaminophen / Propyphenazone
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for the symptomatic treatment of mild to moderate pain such as headaches, toothaches, and menstrual cramps, as well as fever reduction from various causes including infections and inflammatory conditions.

Acetaminophen works primarily in the central nervous system to reduce pain perception and body temperature, while propyphenazone is a non-steroidal anti-inflammatory agent that inhibits prostaglandin synthesis, providing additional analgesic and antipyretic effects.

Should be used with caution in patients with liver or kidney impairment. Alcohol should be avoided during treatment. Not recommended during pregnancy without medical advice. Propyphenazone may rarely cause blood disorders with prolonged use. Do not exceed recommended doses or duration of treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy