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Acetaminophen Salicylamide

Published: July 27, 2026Updated: August 27, 2026

Acetaminophen/Salicylamide is a combination analgesic medication used for the temporary relief of mild to moderate pain and fever. This multi-ingredient formulation combines two pain-relieving agents to provide relief from headaches, muscle aches, backaches, toothaches, and common cold symptoms. The medication is typically taken orally and is available over-the-counter in various strengths.

Quick summary

A combination pain reliever and fever reducer used for minor aches, pains, and fever relief.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
214188
Generic
Acetaminophen / Salicylamide
Class
multi-ingredient
Brands
Frenadol
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves minor aches and pains due to headache, muscle ache, backache, arthritis, toothache, menstrual cramps, and the common cold. Also reduces fever.

Combines acetaminophen (which works primarily in the brain to block pain signals and reduce fever) with salicylamide (a salicylate derivative that provides additional analgesic and anti-inflammatory effects). The combination may provide enhanced pain relief compared to single-ingredient formulations.

Do not use if allergic to acetaminophen or salicylates. Avoid alcohol during use as it increases risk of liver damage from acetaminophen. Consult a doctor before use if you have liver disease, kidney disease, or are taking blood thinners. Not recommended for children without medical advice. Do not exceed recommended dose.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy