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Acetaminophen Styramate

Published: July 27, 2026Updated: August 27, 2026

Acetaminophen/Styramate is a combination medication that pairs a pain reliever and fever reducer with a muscle relaxant. This multi-ingredient formulation is designed to address both pain and associated muscle tension or spasms. It is typically used for conditions where both analgesic and muscle relaxant effects are beneficial.

Quick summary

A combination analgesic and muscle relaxant used to treat pain accompanied by muscle tension or spasms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
823128
Generic
Acetaminophen / Styramate
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

This medication is used to treat mild to moderate pain associated with muscle tension, strains, and spasms. It may also be prescribed for conditions involving both musculoskeletal discomfort and fever, such as tension headaches or post-operative pain with muscle involvement.

Acetaminophen works by inhibiting prostaglandin synthesis in the central nervous system, reducing pain perception and fever. Stryramate acts as a skeletal muscle relaxant, thought to depress central nervous system transmission and relieve muscle spasms. Together, they provide complementary relief of pain and associated muscle tension.

This medication should be used with caution in patients with liver disease, kidney impairment, or a history of alcohol use. Avoid exceeding recommended doses of acetaminophen to prevent liver toxicity. Do not use with other acetaminophen-containing products. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy