Acetaminophen Thiamine
Acetaminophen/Thiamine is a combination medication pairing a common pain reliever and fever reducer with Vitamin B1 (thiamine). This combination is often used in formulations designed for hangover relief or to address thiamine deficiency that may accompany alcohol use, while providing symptomatic relief from headache or body aches. The addition of thiamine helps support proper nerve function and energy metabolism that may be depleted in certain situations.
A combination analgesic and vitamin supplement used for pain relief with thiamine support, commonly associated with hangover formulations.
Key facts at a glance
- RxNorm
- 1007716
- Generic
- Acetaminophen / Thiamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for temporary relief of minor aches, pains, and headaches, often associated with hangover symptoms or alcohol consumption. The thiamine component addresses Vitamin B1 deficiency which may occur with chronic alcohol use or poor nutrition.
Acetaminophen works by inhibiting cyclooxygenase (COX) enzymes in the brain, reducing the production of prostaglandins that signal pain and fever. Thiamine (Vitamin B1) serves as an essential cofactor for enzymes involved in carbohydrate metabolism and proper nerve function.
Acetaminophen can cause serious liver damage if taken in excessive doses or combined with alcohol. Thiamine is generally well-tolerated but high doses may cause mild stomach upset. This medication should not replace proper nutrition or hydration. Consult a healthcare provider if symptoms persist or if you have liver disease, alcoholism, or are taking other medications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy